General Cell Lines and Cell Cultures
Thermo Scientific™ CellSensor™ T-REx™ FOXO3 DBE-bla HeLa Cell Line
The CellSensor™ T-REx™ FOXO3 DBE-bla HeLa cell line was engineered by lentiviral transduction of HeLa cervical cancer cells with a FOXO3 response element driving beta-lactamase expression, along with a tetracycline repressor and tetracycline (or the tetracycline analog doxycycline)-inducible FOXO3 constructs.
Thermo Scientific™ Tango™ HRH3-bla U2OS Cells
The Tango™ HRH3-bla U2OS cells contain the human Histamine Receptor H3 (HRH3) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ MC4R-CRE-bla CHO-K1 Cells
GeneBLAzer™ MC4R-CRE-bla CHO-K1 cells contain the human Melanocortin Receptor 4 (MC4R) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ CellSensor™ p53RE-bla HCT-116 Cell Line
The CellSensor™ p53RE-bla HCT-116 cell line contains a beta-lactamase reporter gene under control of the p53 response element stably integrated into HCT-116 cells.
Thermo Scientific™ CellSensor™ NFAT-bla Jurkat Cell Line
The CellSensor™ NFAT-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a Nuclear Factor of Activated T Cells (NFAT) response element stably integrated into Jurkat cells.
Thermo Scientific™ LanthaScreen™ IkB alpha GripTite™ Cell Line
The LanthaScreen™ IkB alpha GripTite™ cell line contains a fusion protein consisting of the cDNA encoding for GFP and IkB (GFP is fused to the N-terminus of IkB alpha) under the control of a CMV promoter stably transfected into GripTite™ cells.
Thermo Scientific™ Tango™ AGTR1-bla U2OS Cells
Tango™ AGTR1-bla U2OS cells contain the human Angiotensin Receptor 1 (AGTR1) (AGTR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ LanthaScreen™ PDCD4 HEK 293E Cell Line
The PI3K/AKT/mTOR pathway mediates signals for cell growth and survival, transcription and translation, and regulated cell death.
Thermo Scientific™ GeneBLAzer™ M3-NFAT-bla CHO-K1 Cells
GeneBLAzer™ M3-NFAT-bla CHO-K1 cells contain the human Acetylcholine (Muscarinic) Receptor 3 (M3) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ M1-NFAT-bla CHO-K1 Cells
GeneBLAzer™ M1-NFAT-bla CHO-K1 cells contain the human Acetylcholine (muscarinic) subtype 1 receptor (M1) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ HTR2A-bla U2OS Cells
The Tango™ HTR2A-bla U2OS cells contain the human Serotonin Type 2A receptor (HTR2A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ T-Rex™ GPR119-CRE-bla CHO-K1 Cells
The GeneBLAzer™ T-Rex™ GPR119-CRE-bla CHO-K1 cells contain the human G-Protein Receptor 119 (GPR119), stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 Cells
GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 cells contain the human Purinergic receptor P2, G protein-coupled, 11 (P2RY11) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ CXCR6-bla U2OS Cells
The Tango™ CXCR6-bla U2OS cells contain the human Chemokine (C-X-C motif) receptor 6 (CXCR6) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ Tango™ SSTR2-bla U2OS Cells
The Tango™ SSTR2-bla U2OS cells contain the human Somatostatin Receptor 2 (SSTR2) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.